Plasmalogens - For Longevity and Optimal Health
Plasmalogens - Ascidian, Sea Squirt- one marine source for Glycerophosphsolipids for the nervous system
Plasmalogens: For Longevity and Optimal Health
Here is an easy flowing summary if you don’t want to read the detail below:
When we think about ageing well, most of us focus on diet, exercise, and keeping an active mind. But deep inside every cell, there’s another key to resilience and vitality—plasmalogens.
These special lipids are found in high concentrations in the brain, heart, and immune system, where they protect cell membranes, defend against oxidative stress, and keep our systems running smoothly. Unfortunately, plasmalogen levels decline naturally with age, and this drop is linked to memory loss, cardiovascular disease, and immune challenges.
The exciting news? Research shows that replenishing plasmalogens can support longevity, sharper cognition, and healthier aging.
Grey Matter and White Matter: Why Both Matter
Your brain runs on two main engines—grey matter and white matter—and both depend on plasmalogens.
Grey matter is the processing hub, where conscious thought, memory, and decision-making happen. It’s packed with neurons and synapses, and it powers everything from emotions to learning. As we age, synaptic membranes and mitochondria in grey matter become vulnerable to damage.
White matter is the communication network that connects everything together. It’s made of myelinated axons—the “wiring” that ensures signals travel quickly and accurately. With aging and inflammation, white matter breaks down, slowing communication between brain regions.
Supporting both tissues is essential. That’s why Prodrome created two complementary plasmalogen supplements—one targeting grey matter, the other white matter.
Prodrome Neuro™ – The Brain’s Spark
Think of Prodrome Neuro™ as the spark plug for your neurons.
It provides DHA-based (omega-3) plasmalogen precursors, which:
Strengthen synapses and enhance neurotransmission
Boost memory, focus, and learning
Support mitochondrial energy and protect neurons from oxidative stress
Improve circulation and cholesterol balance in the brain and body
Neuro is best taken in the morning, helping keep your mind sharp and responsive throughout the day.
Prodrome Glia™ – The Brain’s Electrician
If Neuro is the spark, Prodrome Glia™ is the electrician maintaining the wiring.
It provides omega-9 plasmalogen precursors (oleic acid), which:
Protect and repair glial cells
Reduce neuroinflammation
Strengthen the myelin sheath, preserving fast signal transmission
Improve sleep, calm anxiety, and support conditions like MS, ALS, and TBI
Glia is usually taken in the evening, giving your brain a chance to repair and restore overnight.
Why You Need Both
Healthy aging isn’t just about preserving memory or keeping your balance—it’s about maintaining the entire communication system of the brain.
Grey matter (neurons + synapses) fuels thought, memory, and cognition.
White matter (myelin + glial support) ensures those thoughts travel quickly and efficiently.
Together, Prodrome Neuro™ and Prodrome Glia™ provide a complete system of support—from spark to signal, from memory to movement.
Key Takeaway
Plasmalogens are more than just cell protectors—they’re essential molecules that help us stay sharp, resilient, and full of vitality as we age. By supporting both grey and white matter, you give your brain the best chance to thrive well into later life.
✨ If you’re looking for a practical way to invest in your longevity, consider starting with Prodrome Glia™ for repair and resilience, then adding Prodrome Neuro™ for sharper cognition.
Table of Contents
Introduction: Why Plasmalogens Matter for Longevity
Plasmalogens and Aging: Protecting the Brain, Heart & Immune System
What Are Plasmalogens? A Simple Guide
The Discovery of Plasmalogens and Its Breakthrough Implications
Plasmalogen Supplementation: Choosing Between Prodrome Neuro & Prodrome Glia
White Matter & Grey Matter: Why Supporting Both Matters
Types of Plasmalogens and Their Functions
Glia Plasmalogens (PE/Ethanolamine-based)
Neuro Plasmalogens (PC/Choline-based)
Omega-9 in Glia vs. DHA in Neuro
Comparison: Prodrome Glia vs. Prodrome Neuro
Key Takeaways: Why Plasmalogens Are Vital for Healthy Aging
Conclusion: Supporting Brain and Body Resilience with Plasmalogens
How to Order Plasmalogen Supplements
Watch: Video Introduction to Plasmalogens
1. Introduction: Why Plasmalogens Matter For Longevity
Plasmalogens are a special class of phospholipids found in high concentrations in the brain, heart, and immune system. They act as protectors of cell membranes, shield against oxidative stress, and support overall vitality. As we age, plasmalogen levels naturally decline, contributing to cognitive decline, cardiovascular disease, and immune dysfunction. Maintaining or replenishing these lipids can play a vital role in longevity and brain health.
2. Plasmalogens and Aging: Protecting the Brain, Heart and Immune System
Plasmalogens are essential because they:
Support Brain Health & Cognition – Aid neurotransmission, memory, and focus.
Slow Aging Processes – Declining plasmalogens are linked with neurodegeneration and chronic disease.
Protect Cell Membranes – Defend against oxidative damage and inflammation.
Boost Heart & Immune Function – Improve cardiovascular resilience and immune balance.
3. What Are Plasmalogens? A Simple Guide
Plasmalogens, a class of specialized lipids found in cell membranes, are gaining recognition for their pivotal role in health and longevity. These molecules are essential for brain function, cellular communication, and overall metabolic health.
Recent research suggests that maintaining optimal levels of plasmalogens may help prevent age-related cognitive decline, improve physical vitality, and support a longer, healthier life.
4. The Discovery of Plasmalogens and Its Breakthrough Implications
Dr. Dayan Goodenowe began his journey into plasmalogen research while studying rare metabolic disorders. He observed that children suffering from a fatal genetic condition—marked by the inability to produce plasmalogens—experienced severe neurological and physical decline.
By creating a synthetic plasmalogen supplement, Dr. Goodenowe was able to replenish these molecules, effectively reversing many of the disorder’s devastating effects. This discovery revealed the profound role of plasmalogens in cellular health and their potential for aging and chronic disease prevention.
5. Plasmalogen Supplementation: Choosing Between Prodrome Neuro & Prodrome Glia
Prodrome Neuro – The Brain’s Spark
Taken in the morning, ProdromeNeuro™ enhances focus, memory, and clarity. It contains omega-3 plasmalogen precursors (DHA) that protect synapses, support mitochondria, and keep cognition sharp.Prodrome Glia – The Brain’s Electrician
Taken in the evening, ProdromeGlia™ helps calm brain inflammation and improve sleep. It provides omega-9 plasmalogen precursors (oleic acid) that nourish glial cells, repair myelin, and support white matter integrity.
👉 Many people benefit from taking both, but Dr. Goodenowe often suggests starting with Glia, then adding Neuro.
6. White Matter & Grey Matter: Why Supporting Both Matters
Your brain is made of two vital tissues—grey matter and white matter. They work together to power every thought, memory, and movement. Both decline with age and inflammation, which is why targeting each with the right plasmalogen supplement is essential.
Grey Matter – The Processing Power
Grey matter contains neurons, the brain’s command centers. It’s where conscious thought, memory, decision-making, and emotion take place.Functions: Memory, learning, emotions, sensory processing
Challenge: Synaptic membranes and mitochondrial energy degrade with age
Supported by: ProdromeNeuro™, which delivers omega-3 plasmalogen precursors to protect synapses and keep neurons firing efficiently.
White Matter – The Communication Network
White matter consists of myelinated axons—long nerve fibers wrapped in insulating myelin. It connects different brain regions, enabling rapid and accurate signal flow.Functions: Coordination, fast communication, brain-body signaling
Challenge: Myelin and glial cell integrity break down with age and inflammation
Supported by: ProdromeGlia™, which provides omega-9 plasmalogen precursors to nourish glial cells and maintain myelin.
Cognitive decline and neurodegeneration involve both white and grey matter. That’s why ProdromeNeuro™ and ProdromeGlia™ work best together—one fuels the processors, the other protects the wiring.
7. Types of Plasmalogens and Their Functions
Glia Plasmalogens (Prodrome Glia™ – PE/Ethanolamine-based)
Target: Glial cells, myelin, white matter
Key Fatty Acid: Omega-9 (oleic acid)
Roles: Protects glia, reduces neuroinflammation, repairs myelin, preserves signal speed
Neuro Plasmalogens (Prodrome Neuro™ – PC/Choline-based)
Target: Neurons, synapses, grey matter
Key Fatty Acid: DHA (Omega-3)
Roles: Enhances neurotransmission, memory, learning, and cognition; protects neurons against oxidative stress
Comparison: Omega-9 vs. DHA
Omega-9 (Glia) – Strengthens myelin, protects glia, maintains white matter
DHA (Neuro) – Enhances synaptic function, supports grey matter, preserves cognition
Prodrome Neuro vs. Prodrome Glia
FeatureProdrome Glia (PE/Ethanolamine)Prodrome Neuro (PC/Choline)Main TargetGlial cells, myelin, white matterNeurons, synapses, grey matterKey Fatty AcidOmega-9 (Oleic Acid)DHA (Omega-3)Primary RoleRepairs myelin, reduces neuroinflammationEnhances neurotransmission, memory, learningBrain FocusWhite matter integrity, communication pathwaysGrey matter resilience, synaptic healthBest ForInflammation, demyelination, white matter declineCognitive performance, memory, cholesterol balanceMetaphorThe Brain’s Electrician (keeps wiring insulated)The Brain’s Spark (boosts signals & connections)
8. Key Takeaways: Why Plasmalogens Are Vital for Healthy Aging
Plasmalogens decline with age, driving cognitive decline and chronic disease.
Glia plasmalogens (Omega-9) protect glial cells, white matter, and myelin.
Neuro plasmalogens (DHA) support neurons, grey matter, memory, and cognition.
Together, they provide whole-brain protection—from processing power to communication networks.
9. Conclusion
Plasmalogens are powerful allies in the fight against aging and cognitive decline. By supporting both neurons (grey matter) and glial cells (white matter), they help maintain a sharp mind, healthy heart, and resilient body.
Prodrome Glia™ (the Brain’s Electrician) and Prodrome Neuro™ (the Brain’s Spark) complement each other to preserve vitality, longevity, and complete nervous system resilience.
10. How to Order Plasmalogens
Order here: Prodrome.com
Coupon Code: CAMPBELL25150 (25% off)
11. Video on Plasmalogens
🎥 Dr. Dayan Goodenowe – Intro and Background [Click here]Dr Dayan Goodenowe -Intro and Background:
10. Conclusion
Plasmalogens are powerful allies in the fight against aging and cognitive decline. By supporting both neurons (grey matter) and glial cells (white matter), they help maintain a sharp mind, healthy heart, and resilient body.
Prodrome Glia™ (the Brain’s Electrician) and Prodrome Neuro™ (the Brain’s Spark) complement each other to preserve vitality, longevity, and complete nervous system resilience.
11. How to Order Plasmalogens
Order here: Prodrome.com
Coupon Code: CAMPBELL25150 (25% off)
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